Spironolactone

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Brand names:

Aldactone®

What is it?

Spironolactone is most commonly used to treat high blood pressure. However, spironolactone has been used for many years to treat disorders such as acne, hirsutism, and androgenic alopecia in women although it is not FDA approved for these conditions.

Does it work?

Spironolactone effectively treats a type of acne called hormonal acne that is often seen in adult women. Spironolactone is a pill that works to stop hormones from causing oil production in the skin. It does not change hormone levels. Spironolactone may take up to 3 months to work.

Things to do during treatment with spironolactone:

Patients are encouraged to drink plenty of fluids, as the drug is a diuretic and will likely increase urination. Failure to drink enough fluids may result in dehydration.

How do I use spironolactone?

Spironolactone can be taken without regards to food. Spironolactone should not be used if you take certain blood pressure medications, have kidney or heart problems, or take any other medications/supplements that can increase potassium.

Side effects:

Menstrual irregularities and increased urination are the most common side effects of spironolactone. Also, some patients experience headaches, dizziness, fatigue, nausea, vomiting and diarrhea. Although very rare, more serious side effects such as hyperkalemia & fetal harm have been reported. You should stop taking spironolactone if you become pregnant.

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Learn more:
Dermatology Times: Spironolactone shows promise for hormonal acne

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